ABSTRACT Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds exhibited potent antiurease activity.

Abstract The present investigation deals with synthesis of new acid dyes from 4-amino-1-(4-sulfophenyl)-3-methyl-5-pyrazolone and phenol derivatives and their metal complexes (Cu (II) and Fe (II)). The phenol derivatives include 4-chlorophenol, 4-nitrophenol, 4-hydroxybenzene sulfonic acid, 2-nitrophenol-4-sulfonic acid, resorcinol and bisphenol A and bisphenol S. The newly synthesized dyes were applied to crust leather to assess their dyeing properties. The fastness properties of unmetallized dyes were less as compared to metal complexes due to the strong interaction of metals with leather protein. The structures of these dyes were also confirmed by UV, FTIR and NMR studies.

Um método mais suave e eficiente é descrito para a síntese de 3-(2'-aminoaril)pirazóis, a partir das reações de 4-cloroquinolinas com hidrazina em excelentes rendimentos. Estas reações de abertura de anel heterocíclico ocorrem em condições mais suaves do que as descritas anteriormente.

We describe a mild and efficient method for the formation of 3-(2'-aminoaryl)pyrazoles in excellent yields from reactions of 4-chloroquinolines with hydrazine. These heterocyclic ring opening reactions occur under much milder conditions then previously described.